Pamela Maher Selected Research

fisetin

2/2021	Preventing and Treating Neurological Disorders with the Flavonol Fisetin.
1/2018	Fisetin Reduces the Impact of Aging on Behavior and Physiology in the Rapidly Aging SAMP8 Mouse.
9/2017	Protective effects of fisetin and other berry flavonoids in Parkinson's disease.
4/2014	Modulation of p25 and inflammatory pathways by fisetin maintains cognitive function in Alzheimer's disease transgenic mice.
5/2012	The flavonoid fisetin attenuates postischemic immune cell infiltration, activation and infarct size after transient cerebral middle artery occlusion in mice.
1/2011	ERK activation by the polyphenols fisetin and resveratrol provides neuroprotection in multiple models of Huntington's disease.
1/2011	Fisetin lowers methylglyoxal dependent protein glycation and limits the complications of diabetes.
10/2007	A novel approach to screening for new neuroprotective compounds for the treatment of stroke.
10/2006	Flavonoid fisetin promotes ERK-dependent long-term potentiation and enhances memory.

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Pamela Maher Research Topics

Disease

28	Alzheimer Disease (Alzheimer's Disease) 03/2022 - 07/2003
17	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 01/2008
13	Inflammation (Inflammations) 01/2020 - 01/2011
7	Ischemia 12/2021 - 10/2007
7	Parkinson Disease (Parkinson's Disease) 02/2021 - 04/2005
6	Stroke (Strokes) 02/2021 - 05/2005
5	Dementia (Dementias) 01/2021 - 09/2012
5	Brain Ischemia (Cerebral Ischemia) 05/2012 - 10/2007
4	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 02/2021 - 01/2008
4	Nervous System Diseases (Neurological Disorders) 02/2021 - 01/2014
4	Memory Disorders (Memory Loss) 01/2020 - 10/2006
4	Cognitive Dysfunction 11/2019 - 01/2011
3	Neuroinflammatory Diseases 01/2021 - 01/2019
2	Huntington Disease (Huntington's Disease) 02/2021 - 01/2011
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2021 - 01/2018
2	Epilepsy (Aura) 01/2019 - 06/2014
2	Neoplasms (Cancer) 01/2018 - 06/2014
2	Ischemic Stroke 01/2015 - 10/2007
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 12/2012 - 01/2011
2	Infarction (Infarctions) 05/2012 - 04/2010
2	Starvation 05/2008 - 07/2003
1	Traumatic Brain Injuries (Traumatic Brain Injury) 02/2021
1	Status Epilepticus (Complex Partial Status Epilepticus) 01/2019
1	Seizures (Absence Seizure) 01/2019
1	Encephalitis (Encephalitis, Rasmussen) 07/2017
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2017
1	Demyelinating Diseases (Demyelinating Disease) 01/2017
1	Disease Progression 01/2017
1	Hypersensitivity (Allergy) 06/2016
1	Central Nervous System Diseases (CNS Diseases) 03/2015
1	Mental Disorders (Mental Disorder) 08/2014
1	Glioblastoma (Glioblastoma Multiforme) 06/2014
1	Relapsing-Remitting Multiple Sclerosis 07/2012
1	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 05/2012
1	Reperfusion Injury 05/2012
1	Cysts 04/2011

Drug/Important Bio-Agent (IBA)

20	Pharmaceutical PreparationsIBA 03/2022 - 04/2005
11	Proteins (Proteins, Gene)FDA Link 01/2019 - 01/2011
9	fisetinIBA 02/2021 - 10/2006
7	Glutamic Acid (Glutamate)FDA Link 01/2019 - 10/2009
7	Glutathione (Reduced Glutathione)IBA 01/2018 - 05/2005
6	J147IBA 03/2022 - 11/2015
6	FlavonoidsIBA 06/2019 - 07/2006
5	Amyloid beta-PeptidesIBA 12/2021 - 07/2003
5	Biological ProductsIBA 01/2020 - 10/2006
5	Neuroprotective AgentsIBA 01/2020 - 10/2007
4	IronIBA 11/2020 - 03/2015
4	Cystine (L-Cystine)IBA 01/2019 - 04/2010
4	Amyloid (Amyloid Fibrils)IBA 08/2014 - 05/2008
3	Peptides (Polypeptides)IBA 01/2020 - 01/2009
3	AntiportersIBA 01/2019 - 04/2013
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2018 - 12/2012
2	Fatty Acids (Saturated Fatty Acids)IBA 03/2022 - 07/2017
2	3-hydroxyflavoneIBA 02/2021 - 01/2018
2	CopperIBA 11/2020 - 01/2018
2	CalciumIBA 01/2020 - 04/2013
2	AntioxidantsIBA 01/2020 - 01/2018
2	Interleukin-13IBA 01/2020 - 06/2016
2	LipidsIBA 01/2020 - 07/2009
2	Adenosine Triphosphate (ATP)IBA 01/2018 - 02/2008
2	Therapeutic UsesIBA 01/2018 - 01/2011
2	Advanced Glycation End ProductsIBA 01/2017 - 09/2013
2	CytokinesIBA 06/2016 - 12/2012
2	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2014 - 05/2008
2	EnzymesIBA 04/2011 - 01/2011
2	Glucose (Dextrose)FDA LinkGeneric 05/2008 - 07/2003
1	taxifolinIBA 01/2020
1	Fatty Acid Synthases (Fatty Acid Synthase)IBA 01/2020
1	Interleukin-6 (Interleukin 6)IBA 01/2020
1	CannabinoidsIBA 11/2019
1	Sulfasalazine (Azulfidine)FDA LinkGeneric 01/2019
1	Anticonvulsants (Antiepileptic Drugs)IBA 01/2019
1	Pilocarpine (Ocusert)FDA LinkGeneric 01/2019
1	SenotherapeuticsIBA 12/2018
1	EstersIBA 02/2018
1	ferulic acid (sodium ferulate)IBA 02/2018
1	Mitochondrial Proton-Translocating ATPases (Mitochondrial ATP Synthase)IBA 01/2018
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2018
1	Homer Scaffolding Proteins (Homer 1)IBA 01/2018
1	1-Methyl-4-phenylpyridinium (1 Methyl 4 phenylpyridinium)IBA 01/2018
1	Pyruvaldehyde (Methylglyoxal)IBA 01/2017
1	Amyloidogenic ProteinsIBA 01/2017
1	DeferiproneIBA 03/2015
1	Chelating AgentsIBA 03/2015
1	Ionotropic Glutamate ReceptorsIBA 01/2015
1	Analgesics (Analgesic Drugs)IBA 08/2014
1	Phosphatidylinositols (Phosphatidylinositol)IBA 06/2014
1	Cysteine (L-Cysteine)FDA Link 06/2014
1	Peptide Initiation Factors (Initiation Factor)IBA 06/2014
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 06/2014
1	Activating Transcription Factor 4IBA 06/2014
1	Streptozocin (Streptozotocin)FDA Link 12/2012
1	Dimethyl FumarateIBA 07/2012
1	LipopolysaccharidesIBA 05/2012
1	PolyphenolsIBA 01/2011
1	ResveratrolIBA 01/2011

Therapy/Procedure

4	Therapeutics 01/2021 - 01/2019
1	Traditional Medicine (Folk Remedies) 01/2020
1	Electrodes (Electrode) 01/2019
1	Oral Administration 04/2014